**α-Mangostin: Science-Backed Benefits of a Tropical Supercompound** α-Mangostin is a naturally occurring xanthone compound found predominantly in the pericarp (rind) of the mangosteen fruit (*Garcinia mangostana*), a tropical plant native to Southeast Asia. Renowned in traditional medicine, modern science has validated its antioxidant, anti-inflammatory, and antimicrobial properties, making it a subject of interest for wellness and skincare formulations. **Key Properties & Research Insights** 1. **Antioxidant Power**: α-Mangostin neutralizes free radicals, reducing oxidative stress linked to aging and cellular damage (studies: *Journal of Natural Products*, 2010). 2. **Anti-Inflammatory Effects**: It inhibits pro-inflammatory cytokines, suggesting potential for managing chronic inflammation (*International Immunopharmacology*, 2015). 3. **Skin Health**: Topical applications may support collagen synthesis and UV protection (*Cosmetics*, 2018). **Safety & Usage** While generally recognized as safe (GRAS) in extracts, consult a healthcare provider before supplementation. Typical sources include standardized mangosteen extracts or whole-fruit powders. **Conclusion** α-Mangostin exemplifies nature’s synergy with science. Its multifaceted benefits, coupled with a need for further clinical trials, position it as a promising—but not miracle—ingredient for holistic health.